6 results
To assess the PK/PD relationship of prednisolone regarding toxicity as clinical outcome in paediatric patients with autoimmune or autoinflammatory diseases
Critical illness, along with the lack of zeitgebers on the PICU environment, and iatrogenic influences like medication and procedures, results in disturbed circadian rhythms in critically ill children, which is important for their recovery.
To assess the PK/PD relationship of prednisolone as either prophylaxis or therapy of GVHD in children after HCT.
This research aims to determine factors involved in subfertility and serious pregnancy complications that arise early in pregnancy. Due to increased insight into the pathogenesis of these conditions, primary prevention should ultimately be possible.
Investigate the effect of having CYP2C19 and CYP2D6 genotypes at start of antidepressant therapy and it’s cost-effectiveness in the primary care setting.
We expect that the use of the flexible IM rod results in a post-operative sagittal contour of the distal femur that resembles the pre-operative situation, i.e. a better fit of the prosthesis, when compared to the use of the the standard IM rod