1101 results
Several investigators have suggested using dietary carbohydrate restriction as a therapeutic strategy to allow the host to successfully compete against a tumor [2, 7, 19]. The induced ketosis and increased lipolysis after low carbohydrate diets have…
Recurrent miscarriages is defined as three or more consecutive miscarriages prior to the 20th week of gestation. Whenever the diagnosis ‘recurrent miscarriages’ is established, an underlying cause may be identified in about 25-50% of cases. A…
A higher percentage of patients with MRD levels <0.1% (MRD negativity) after up to 2 courses of induction chemotherapy plus quizartinib, as measured in the bone marrow using MFCM before start of consolidation therapy, compared to a historical…
The primary hypothesis for this data collection study is that there are various surrogate physiological parameters for inferring blood pressure (BP), which can be more easily obtained than the direct BP measurement. An example of such surrogate…
Prevention of the progression of TMD to ML-DS by chemotherapeutical profylaxis can be possible.
Two hours of end-ischemic hypothermic oxygenated perfusion via both the hepatic artery and the portal vein is feasible and safe in resuscitating liver grafts procured from donation after circulatory death donors.
By measuring biomedical variables, such as movement, temperature, heart rate variability, blood volume pulse and skin conductance, by means of a wearable (wristband), stress-related parameters can be measured easily and continuously. It is…
Chronic heart failure (CHF) is a clinical syndrome resulting from a decreased cardiac output, insufficient to maintain adequate tissue oxygenation. Eventually, inadequate tissue oxygenation will lead to pathological alterations, especially at the…
What are the motivations of women in the Netherlands to choose UC and what are their beliefs on childbirth in general and in relation to current Dutch maternity care? This study primarily aims at understanding women’s motivations in declining (parts…
Since progression from NAFLD to NASH is associated with significantly increased risk of morbidity and mortality, there is a clinical imperative to identify the NAFLD patients that rapidly progress to NASH from those who will remain in the NAFLD…
It is expected that the respiratory microbiome will be relatively stable over time in non-infectious patients.
DBS-related cognitive decline and psychiatric side-effects in Parkinson's disease (PD) patients can be studied from a functional- and structural network point of view. We will characterize functional and structural brain networks in PD patients…
Does sildenafil improve tumour perfusion?
A mathematically correct PK-PD model will be developed that describes the depressant effect of propofol on breathing with and without a background of remifentanil.
We hypothesize that selfmanagement support via an internet based service in addition to usual care will improve health related quality of life in patients with severe asthma who have participated pulmonary rehabilitation in specialized asthma…
•To assess the safety and tolerability of induction doses of ABP-700 and determine dosing regimens that reliably produce drug induced unconsciousness and the pharmacodynamic conditions necessary for induction of general anesthesia with ABP-700 alone…
Circulating tumour cells can help to diagnose Non small cell lung cancer (NSCLC), making the painful and invasive procedure of a lungbiopsy and bronchoscopy unnecesary. However, for this, we need to harvest higher amounts of CTC's and in more…
Psychological risk factors will cluster in multiconstruct patient profiles predicting outcome. A network of biological and behavioral mechanisms explain the relationship between these psychological risk clusters and outcome after PCI. The ESC…
The null hypothesis will be that the prevalence of bruxism and TMD, in PD patients will be higher than in their peers without PD. Also, we hypothesized that factors as medication use, disease severity, psychosocial factors and lifestyle factors are…
Patients will improve significantly on OCD symptoms and general functioning.