280 results
The overall aim of this study is to generate a first impression about the usability of the therapy-supportive Luca app with youngsters in youth mental healthcare. For this purpose, we will ask the following research questions: 1. How do therapists…
HIV-infection and antiretroviral therapy use may lead to a diminished neurological and neurocognitive performance in HIV-infected children.
Since several years, anti-VEGF agents have become available for the treatment of neovascular age-related macular degeneration (AMD) and have substantially improved visual prognosis in patients suffering from this condition. The anti-VEGF agent used…
We hypothesize that general practitioner (GP) involvement improves both aftercare and preventive care resulting in improved quality of life and patients’ satisfaction. Furthermore, a GP-led recurrence detection programme leads to at least equal…
We hypothesize that telephone aftercare for patients of 70 years and older within 24 hours after discharge to a home setting from the ED will lead to a reduction in hospital admission, in avoidable, unanticipated hospital admissions and ED visits…
We hypothesize that by combining the recently validated gout flare criteria with a patient-friendly app and real-time monitoring, we can implement a gout flare measure that is less prone to recall bias and can be used by patients at home. It could…
Our hypothesis is that patients who are denied of ERCP during initial hospital admission, will be more frequently readmitted because of recurrent biliary events compared to those who did undergo ERCP during primary hospital admission.
We hypothesize that the combination of both the IPS and PA intervention is more effective than each of the interventions separately (IPS, or PA), i.e. ‘1+1 = 3’
By developing a model which predicts the risk of bleeding with coumarin use, patients can be treated more effectively, potentially avoiding the need for specific antidotes. Besides decreasing the risk of bleeding (potentially resulting in less…
The goal of this study is to determine whether radiosensitization with carboplatin or the addition of Isotretinoin to maintenance therapy improves cure rates for children with other than average risk medulloblastoma/PNET.
Technology applied to physiotherapy could contribute to identify subgroups in non-specific low back pain patients.
To determine the epidemiology, diagnosis and prognosis of enterovirus (EV) and parechovirus (HPeV) infection in Dutch children. Hypotheses: 1. EVs are one of the most important viral agents of infection in Dutch children; 2. EVs are the major cause…
Natural killer cells are cells of the innate immunesystem and can kill tumor cells without prior sensitization. By infusing these cells through a catheter in the intraperitoneal cavity, ovarian carcinoma cells can be traced and killed. This phase 1…
Combination therapy with telaprevir/ ribavirin is as effective as the current standard of care with peginterferon-alfa/ ribavirin for the treatment of acute Hepatitis C in HIV-infected individuals.
To investigate the possibility to predict chemotherapy response using proliferation assays.
Combination of a round window insertion approach and a lateral wall electrode array minimizes insertion trauma
Octreotide, a somatostatin analog that preferentially binds with sst2, is frequently used in the treatment of somatotropic pituitary adenomas and neuroendocrine tumors. The glucocorticoid-mediated sst2 downregulation in corticotroph adenoma cells…
1. What are characteristic (neuro)physiological factors of fatigue in disease-free cancer patients? 2. To which degree can these factors be influenced by Cognitive Behavior Therapy?
What is the prevalence of dysplasia or carcinoma in patients with Crohn's disease that undergo surveillance endoscopy with chromoendoscopy-guided confocal laser endomicroscopy?
The manual knee-rotation-test in 90 degree flection is reliable