110 results
Natural killer cells are cells of the innate immunesystem and can kill tumor cells without prior sensitization. By infusing these cells through a catheter in the intraperitoneal cavity, ovarian carcinoma cells can be traced and killed. This phase 1…
Addition of alternative tests (TEG/ROTEM® and/or TGA) which reflect the whole hemostatic status of a patient might help recognizing the level of thrombin formation and fibrinolysis and improve care in ECMO patients and potentially reduce the risk of…
What is the prevalence of dysplasia or carcinoma in patients with Crohn's disease that undergo surveillance endoscopy with chromoendoscopy-guided confocal laser endomicroscopy?
Chemodenervation by lidocaine of the m. vastus intermedius and the m. rectus femoris improves gait pattern in stroke patients presenting a stiff knee gait.
1. What are characteristic (neuro)physiological factors of fatigue in disease-free cancer patients? 2. To which degree can these factors be influenced by Cognitive Behavior Therapy?
Recently, (changes in) the gut microbiome (flora / bacteria) have been associated with obesity and insulin resistance, and other cardiovascular risk factors or atherogenic processes. Venous thrombosis shares these risk factors, probably by a shared…
In this RCT we investigate the effects of two school-based physical activity interventions (aerobic exercises versus coordinative exercises) in primary school children on executive functions and academic achievement. We hypothesize that both aerobic…
HIV-infection and antiretroviral therapy use may lead to a diminished neurological and neurocognitive performance in HIV-infected children.
We hypothesize that, with increased arm abduction moment loading with a constant exerted abduction force, primary arm moment generators (deltoid muscle) will have a greater increase in activation (EMG) as compared to primary arm/glenohumeral…
Since several years, anti-VEGF agents have become available for the treatment of neovascular age-related macular degeneration (AMD) and have substantially improved visual prognosis in patients suffering from this condition. The anti-VEGF agent used…
We hypothesize that telephone aftercare for patients of 70 years and older within 24 hours after discharge to a home setting from the ED will lead to a reduction in hospital admission, in avoidable, unanticipated hospital admissions and ED visits…
Sunitinib, when given in a high-dose, intermittent schedule, may exhibit improved efficacy with an acceptable toxicity profile.
It is hypothesized that both positive verbal suggestions regarding an inert substance and a positive imagery exercise result in a lower sensitivity to physical sensations (pain, itch, and fatigue) than neutral verbal suggestions and/or neutral…
No improvement of fixation failure will be found after the introduction of the TFNA
Biomarkers like MR-proADM and CT-proAVP predict severity and outcome in critically ill COVID-19 patients. MR-proADM and CT-proAVP at admittance can be higher in non-survivors and biomarker clearance over the days will be higher in survivors.
Bipolar radiofrequency lesioning of the thoracic medial branch of the dorsal ramus is more effective than a monopolar radiofrequency lesion
Online treatment based on imagery rescripting is effective in the treatment of nightmares
The temporal artery biopsy has no additional value after a halo sign using ultrasound of the temporal artery
We hypothesize that the combination of both the IPS and PA intervention is more effective than each of the interventions separately (IPS, or PA), i.e. ‘1+1 = 3’