142 results
The administration of propranolol will inhibit the increase in dermal blood flow (DBF) induced by capsaicin application.
The hypothesis is that E171 induces inflammation in the colon, and that the inflammatory condition would facilitate the development of colorectal cancer
Reduced dermal blood flow response to capsaicin application and saline iontophoresis after propranolol ocompared to placebo administration.
This study aims to evaluate the effect of order of carbohydrates, protein and fat intake on postprandial blood glucose levels in children with type 1 diabetes. Our hypothesis is that postprandial blood glucose levels, measured by capillary blood…
In normal weight and overweight/obese young males we expect that - when compared to a single bout of prolonged sitting: (1) sitting on a stability ball will attenuate cardiometabolic health effects; (2) 10-min standing interruptions will not…
With a recently developed Ara h6 ELISA we would like to show the effect of exercise on circulating Ara h6 after peanut consumption
In a series of randomized control trials (RCTs) the following hypothesis will be tested: Intranasal administration of oxytocin and vasopressin affect neural and behavioral responses to infant signals and threat to the infant.* Oxytocin and…
To determine the mechanism of action of propranolol in the prophylactic treatment of migraine.
The primary objective of this study is to investigate the effect of a single dose of L. Barbarum on postprandial energy expenditure. Secondary objectives are to investigate the effect of a single dose of L. Barbarum on postprandial lipid and…
Primary objective- To explore the pharmacodynamic effects of topically applied IMQ (in combination with or without TS) - To identify dose-response relationship of topically applied IMQ Secondary objective- To assess safety and tolerability of…
Primary objective of this study is to assess changes in brain connectivity and activity in the Default Mode and Salience Network (hypothalamus, prefrontal cortex, nucleus accumbens, Ventral Tegmental Area) after different sugars and sweeteners.
To determine the prevalence and severity of ASA-related allergic reaction in SM patients.
The aim of this study is to assess the influence of alveolar tampon packing on incidence of pain, swelling, trismus, alveolar osteitis, and QoL in the week following M3 surgery.
Primary ObjectiveThe primary objective is to investigate the PK of the MMF * the main metabolite of DMF * following administration of a delayed-and slow-release tablet formulation (FP187-GC) and the marketed enteric-coated delayed release…
Primary objectives: this study will 1) assess the accuracy of the Cortex MetaLyzer® 3B in adolescents (12-17 yr) for measuring REE, using the Deltatrac® II metabolic monitor as a reference; and 2) assess the accuracy and the within-subject, within-…
Primary objective: Assessment of the impact of the reference glucose measurement on the measured performance of a CGM system, comparing regular venous and arterialized-venous reference glucose samples.Secondary objective: - Assessment of the impact…
The primary objective of this confirmatory study is to investigate the acid neutralisation action of Gaviscon Double Action Tablets versus placebo tablets, within the stomach.The secondary objective of this study is to assess the safety of the test…
Primary:• To demonstrate the therapeutic equivalence of ONS-3010 (adalimumab biosimilar) compared toHumira® (adalimumab) in patients with plaque psoriasis Secondary:• To assess the safety, tolerability, and immunogenicity of ONS-3010 compared to…
In this study we therefore investigate the influence of prednisone on docetaxel exposure in metastatic prostate cancer patients.