54 results
DBS in the nucleus accumbens can lead to long-term improvement of obsessive-compulsive symptoms and funtioning, without unacceptable side-effects.
Cholesterol lowering by low fat diet and lovastatin will also reduce very long chain fatty acids in patients with X-ALD.
Improvement of the intestinal microflora of children consuming a fibre-enriched versus a standard paediatric tube feed.
The time constant of oxygen uptake during recovery of submaximal exercise is a reliable parameter to measure effects of exercise training in patients with chronic heart failure.
Cross-transmission of antibiotic-resistant pathogens can be prevented by using closed suction systems (CSS) instead of open suction systems (OSS) in mechanically ventilated ICU patients.
The aim of this study is to prove the efficacy of 3 times daily 1 mg glycopyrronium bromide versus placebo in patients with PD with hypersalivation. Furthermore, the safety of glycopyrronium bromide used in the mentioned dosage will be further…
STUDY OBJECTIVESTo determine whether NAC therapy results in decreased red cell PS exposure, endothelial activation, inflammation, and reduction clotting activation in the steady state.
The application of CGMS offers novel possibilities to define the impact of different exercise parameters like exercise duration, frequency and intensity on glycemic control in type 2 diabetes patients. In addition we are interested in the impact on…
The sequential application of chemotherapy and radionuclide treatment in patients with symptomatic osseous metastasized prostate cancer. Patients with more than one painful osseous metastasis will be randomized between 153Sm-EDTMP or docetaxel 3…
Part 1 of the study has two objectives. Firstly, we will study the safety and tolerability of the drug after the administration of single ascending oral doses of the drug. Secondly we will study the pharmacokinetics and pharmacodynamics. This means…
A pilot study to:1. assess the urodynamic changes induced by 100mg MR formulationof UK-369,003 vs. placebo in men with LUTS;2. Assess the safety and tolerability of UK-369,003 in men with LUTS
To test this hypothesis by administering inhaled isotonic magnesium sulphate to patients with stable severe asthma and persistent airflow obstruction (postbronchodilator FEV1 < 75% predicted) and determine the bronchodilating effect by…
To determine the association between the development of sensory specific satiety and intensity of oral sensory stimulation. Specifically, the development of SSS after consumption of a bar shaped snack vs. a nibble shaped snack of similar ingredients…
To determine the differential effect of age (children vs. adults) on the development of sensory specific satiety (SSS) in relation to intensity of drinks (both sweetness and flavour). To compare two methods of assessing SSS.
To determine the specificity of the effects of histamine H1-receptor blockade on different cognitive functions and processes.
Aim: The aim of the present study was to evaluate the effect of 3 manual toothbrushes with regular and soft filament designs in relation to gingival abrasion and plaque removing efficacy
1. To test feasibility of mannitol inhalations in a Dutch pulmonary out-patient clinic.2. To compare time and costs involved in measuring airways hyperresponsiveness by methacholine to mannitol
The aim of this study is to investigate the efficacy, accuracy and patient satisfaction of intra-articular injections in the osteo-arthritic ankle joint using the traction device compared to the conventional method of injecting.
In this study, the effects of low-fat dairy products on metabolic risk markers in subjects at increased risk of metabolic disorders are determined.
Investigate the optimal dose of such an insulinotropic mixture.