528 results
Trifluridine is primarily metabolized through degradation by thymidine phosphorylase to the inactive metabolite 5-(trifluoromethyl)-uracil (FTY) without any involvement of the cytochrome P450 enzyme system. The primary route of excretion of…
Interaction between oral dexamethasone and aprepitant is different than the interaction between iv dexamethasone and aprepitant.
Grasping performance of daily life grasping tasks will be improved when vibrotactile feedback about the hand opening and grasping force is provided compared to situations without vibrotactile and visual feedback.
The stimulant effects of caffeine result in its common consumption by individuals in an attempt to combat the detrimental effects of fatigue on performance. However, inconsistent findings regarding the effects of caffeine on cognitive performance…
A self help brochure will help people decrease their excessive worrying. and telephonic support will increase the effect.
The intention to change behavior is related to changes in multiple physiological variables. Thermal comfort and thermal sensation are related to these physiological parameters. Furthermore, the intention of behavior is related to changes in thermal…
In this study we will compare three method to assess the magnitude of the ventilatory response; our hypothesis is that different methods will yield different results.
Main hypothesis The BENEFIT intervention will significantly increase the number of CVD patients that can maintain the healthy lifestyle behavior most relevant to them for at least one year, compared to care-as-usual. Secondary hypothesis The BENEFIT…
A motor activation program benefits the number of motor activities which can improve several domains of human functioning
1. Inhaltion of tobramycin containing aerosols using the INeb® in the TBM mode is less effective as inhalation of in the TIM mode; 2. The amount of deposition is correlated to the systemic Area Under the Curve of tobramycin after inhaltion of…
1. SMOFlipid® decreases peripheral insulin sensitivity to a lesser extent compared to the other lipid emulsions, Intralipid® and Clinoleic®, due to the lower n6/n3 ratio and the higher MCT concentration in the SMOFlipid emulsion; 2. SMOFlipid®,…
The study of determinants of cardiovascular disease (CVD) is important because it provides insight in risks and opportunities to reduce the burden of CVD. A major gap in our current knowledge about CVD lies in the way we measure these determinants,…
B2-agonists can increase CFTR function and improve disease parameters in patients with CF with a residual CFTR function. Multiple patient-specific parameters are important for the amount of B2-agonist induced CFTR function, measurements in organoids…
We hypothesize that there is no difference between the survival and follow of the uncemented and cemented ABG THA.
This study aims to investigate the effectiveness of a multicomponent intervention in promoting physical activity among adults with ID.
To evaluate the effects of a versatile web-based health game on cognition and compliance in Parkinson’s disease with mild cognitive impairment.
We hypothesise that fasting-induced insulin resistance will result in decreased glucose uptake and activity of brown adipose tissue (BAT). In addition, prolonged fasting will lead to reduced mitochondrial uncoupling in skeletal muscle, which is…
Objective: To assess the diuretic effect of three standard glasses of beer, red wine and spirits in euhydrated elderly men.
With a recently developed Ara h6 ELISA we would like to show the effect of exercise on circulating Ara h6 after peanut consumption