672 results
To investigate whether amino acid area under the curve (AUC) and Cmax of product B is equivalent to amino acid AUC and Cmax of product A
It is hypothesized that use of PERSARC leads to significantly less decisional conflict in patients and more informed decisions compared to usual care (treatment decisions without use of PERSARC) by reducing the uncertainty regarding risks and…
ETMI improves the detection of early neoplasia in Barrett's esophagus.
Cast treatment is not inferior to surgical open reduction and internal fixation in terms of patient related outcome measurements.
Due to the lack of information about DON absorption and excretion, the aims of this study are the description of the DON and metabolites excretions patterns and know the absorption and excretion rates of it. Moreover, the results can be useful to…
Infant formulae with higher levels of milk fat result in improved fatty acids absorption as compared to standard formula.
Acid-reducing drugs, such as PPIs, may profoundly decrease solubility and, as a result, (negatively) affect the bioavailability of afatinib. Since a PPI is often used concomitantly during afatinib therapy, this DDI confronts physicians, patients,…
The hypothesis is that alpha2-adrenergic receptors play an important role in bone remodeling.
increased gastric distention will induce greater activation in satiety related areas
Smart energy meter data used in a monitoring system to alert users when out-of-the-ordinary activity is detected, may improve health-related quality of life and perceived safety of community-dwelling older persons and their informal care providers.
To investigate if flavour nutrient learning is an effective mechanism to increase children's vegetable intake. Is there an effect?
The primary objective of the present study is to assess efficacy of DBS in the nucleus accumbens for patients with refractory MDD. Secondary objectives are the evaluation of long term efficacy and tolerability of DBS for patients with therapy…
In the current study, we will construct utility functions of two opioids, tapentadol and oxycodone, to assess the benefit/harm ratio of these drugs. To that end we will perform a PK PD study in healthy volunteers
We expect to find little to no uptake of curcumin in the central circulation.
Non-invasive ventilation reduces the inflammatory response to exercise.
It is hypothesized that foods that have an intrinsic nutrient-rich matrix are less susceptible to changes in reward value due to replacing the sugar content than foods that have intrinsic a nutrient-empty matrix. Thus we expect that the reward value…
The use of automated closed loop oxygen control in infants on infants with high flow nasal canulla (HFNC) support, will lead to higher amount of saturations within target range compared to manual control.
Fentanyl is highly lipophilic. Localizations with a thicker fatlayer absorp more fentanyl than localizations with a thinner fatlayer. When patients stick the patch in different localizations this can lead to different concentrations of fentanyl.…
Are there effects of ARA290 and Epo on the ventilatory response to hypoxia. Are there effects of ARA290 and Epo on the gradient over the tricuspid valve during hypoxia a an estimation of the pulmonary artery pressure (PAPA). Does ARA290 and/or Epo…