648 results
1. To examine the effect of cold on post-prandial triglyceride metabolism using a standardized meal test during and after cold exposure 2. To examine the relationship between cold-induced brown adipose tissue activity and the changes in…
The specific mechanism of inhibition differs between SST variants, it remains the question why. Our envisaged study focuses on this question. We expect that the difference is caused by the amount of perceptual overlap between the go stimulus and the…
The main objective of the study is to determine the albuminuria lowering effect of the GLP1-RA exenetide, SGLT-2 inhibitor dapagliflozin and their combination in patients with type 2 diabetes and micro- or macroalbuminuria.Secondary objectives are…
The primary objective is to assess the relative bioavailability of iron from insect added to either a high- or low-phytate meal in humans and its potential to provide bioavailable iron. The secondary objective is to determine whether addition of…
The main objective of the present study is to investigate whether it is possible to use the VOC pattern in exhaled air as a parameter of metabolism of lipids.Primary Objective: To investigate the difference in postprandial change in volatile organic…
The main objective of this study is to assess the efficacy of the closed loop system over an extended period. Secondary objectives are to assess the safety of the closed loop system; to determine the time that the control algorithm is active; to…
The primary objective is to investigate the effects of dopamine receptor stimulation on neural and behavioural measures of perception and consciousness. The secondary objective is to establish the relation between the effects of dopamine stimulation…
The current study will examine the safety and pharmacokinetic profile of JWH-018.
The primary objective of this study is to compare pain suppression in two groups of subjects with chronic unilateral limb pain as a result of FBSS. Low Frequency spinal cord stimulation settings and High Frequency spinal cord stimulation settings…
The main objective of the study is to investigate if nicotinamide riboside supplementation can improve whole body and hepatic insulin sensitivity in overweight and obese men and women. As secondary objectives we want to investigate if nicotinamide…
Primary objective:- To evaluate the effect of JZP-110 on driving performanceSecondary objectives:- To evaluate the safety and tolerability of JZP-110- To explore SAFTE (Sleep, Activity, Fatigue, and Task Effectiveness) modeling using driving,…
A better understanding on the individual response to different albuminuria lowering drugs and a better understanding why these drugs, of which some are developed for another indication, may help to tailor optimal therapy. Therefore in this study…
To verify whether the emotional valence of the distracting task will affect the effects of the dual tasking procedure in a help seeking PTSS population.
To examine the effects of a treatment that consists of different natural ingredients on cognitive performance in…
Primary objective: To accurately assess the direct functional consequences of high versus low phenylalanine levels in adult patients with PKU, using eye-hand coordination testing in tasks of different cognitive complexity. Secondary objective: To…
This study aims to determine the digestibility of AAs in two protein sources in men and women with normally functioning ileostomies.
Objectives: The primary objectives are: to determine if there is a perceivable difference between plain and FAAA-enriched versions of selected food products and describe sensory and/or hedonic differences between them; to assess the dependency of…
To study gastric emptying of breastmilk and infant formula and to see whether gastric emulsion stability differs between breastmilk and infant formula.
Primary objective: - To measure infraslow EEG changes during stress response in healthy subjects.Secondary objective(s):- To investigate if cortisol levels relate to ISA.- To explore ISA activity as a potential biomarker for stress.- To formulate…
The effects of macronutrients on postprandial vascular function in overweight and slightly obese men
The primary objective of the proposed study is to evaluate the effect of the three macronutrients on postprandial vascular function, assessed by brachial artery flow-mediated vasodilation (FMD), in overweight and slightly obese male volunteers.…