663 results
The objective of the study is to diminish the amount of chemotherapy and/ or radiotherapy for children with Hodgkin lymphoma who are likely to receive too much treatment with current treatment protocols.
The goal of this study is to determine whether radiosensitization with carboplatin or the addition of Isotretinoin to maintenance therapy improves cure rates for children with other than average risk medulloblastoma/PNET.
To compare the EEG pattern after administration of cyclopentolate with the EEG pattern after placebo eye-drops.Primary outcomeEEG pattern changes after administration of two drops of cyclopentolate1% compared with placebo.Secondary outcomes- Pattern…
Determine efficiency and safety of two different doses of pregabalin as compared to placebo.
Studying the effect of two intervention programs (1. Motor Imagery Training, 2. Cognitive Orientation to Daily Occupational Performance (CO-OP)) on the motor abilities, motor imagery and motor planning capacities in children with Developmental…
To determine whether computerized training procedures can lead to a decrease of aggression-related attention andinterpretation, and whether this reduces aggressive behaviors.
Determining the long-term (18 months) effectiveness and cost-effectiveness of an elimination diet (ED) as the first addition to care as usual (CAU) in comparison to providing CAU only in children with ADHD (5-12 years). Hypotheses: Long-term…
Primary objective of this study is to investigate whether EEG can be used to predict future febrile or afebrile convulsions. Secondary objectives of this study are to investigate the influence of EEG on antiepileptic drug prescription (will…
Primary objective: To investigate the effectiveness of ongoing treatment with methylphenidate as prescribed in clinical practice beyond two years in children and adolescents. Secondary objectives:(1) to investigate the effects of discontinuation of…
Primary Objective:To evaluate the effect and sustainability over time of behavioural treatment for sleep problems in children with AS on the actual hours of sleep and sleep behaviour of the children.Secondary Objectives:To evaluate the effect and…
Specific AimsAs reviewed above, childhood anxiety disorders are highly prevalent and debilitating, and there is an urgent need for improvement of current treatment strategies. An innovative, but scarcely examined, treatment option for childhood…
The primary objective of this study is: To study the effect of controlled discontinuation of long-term used risperidone, for the treatment of challenging behavior, on behaviour and health. Our hypothesis is that long-term use of risperidone for…
The main objective of this study is to investigate whether a music intervention as complementary treatment is effective in reducing anxiety and distress around surgery. Secondary objectives are effects of music on pain, on preoperative anxiety, on…
If the study shows that the treatment with a sling gives an earlier return to normal function en does not give a clinically significant difference in pain experience compared to cast therapy than the traditional treatment can be adjusted. We aim at…
The main objective is to compare the coronal Cobb angle correction of proximal hook claw fixation versus proximal pedicle screw fixation after two years of follow-up. The secondary objectives of the study are: comparison of coronal Cobb angle…
The main objective of the study is to evaluate the efficacy of the *Blended Coping Cat* program in reducing anxiety levels in children diagnosed with anxiety disorders and possible ADHD, ASD, mild intellectual disability or borderline intellectual…
Primary, this study investigates the effect of VR on procedural pain. Secondary, this study investigates the effect of VR on satisfaction with the procedure, identifies patient-related, burn wound-related and psychology-related variables associated…
To compare the clinical outcome of daily showering followed by immediate application of emollient to once weekly showering followed by immediate application of emollient, in children with mild to moderate AD. The primary outcome parameter will be…
To evaluate the impact of electroencephalographic NarcotrendTM Index (NI) monitoring on the speed of emergence and recovery from PPS for PGE.