237 results
We expect that the access-related intervention rate and medical costs will be reduced by 40% when correction of vascular access stenosis is triggered by clinically apparent access dysfunction rather than by asymptomatic flow reduction detected by…
In patients with ANOCA, identification of specific endotypes of vascular dysfunction with intracoronary testing, followed by pharmacological and nonpharmacological interventions aligned to the identified endotype, leads to better control of angina…
An activity tracker improves preoperative gait speed in elderly colorectal cancer patients compared to a standard prehabilitation program
Non-inferiority of omission of PCI prior aortic valve replacement by TAVI
Part 1 Single Ascending Dose (SAD) - To evaluate the safety and tolerability of a single oral dose of prodrug, ABX-002, in healthy adult subjects Part 2 Multiple Ascending Dose (MAD) -To evaluate the safety and tolerability of once daily oral…
The course of resting energy expenditure (REE), measured by indirect calorimetry changes based on standard versus high enteral protein feeding in the ICU.
We hypothesize more than 90% of the participants in the in-hospital, standard-of-care follow-up will contact the hospital during the study period and 40-50% of the patients in the patient-led, home-based follow-up will contact the hospital between…
Primary hypothesis: PCT with oNCRT will lead to a larger decrease in depressive symptoms (measured with the IDS-SR) over the course of one year, as compared to PCT alone. This is a two-tailed hypothesis, where the effect of PCT + oNCRT relative to…
We hypothesize that the use of this algorithm will reduce hypotension as measured by the time weighted average (TWA) during both the off-pump phase of on-pump coronary artery bypass graft (CABG) surgery and the mechanically ventilated phase of post-…
The hypothesis of the TRANSFORM II study is the non-inferiority of Sirolimus Coated Balloon versus Everolimus Eluting Stent in terms of Target Lesion Failure
The aim of this study is to demonstrate that a single dose of rabies vaccine can induce an equally rapid and adequate anamnestic antibody response as 3-dose PrEP to revaccination five years later.
Screening for AF, using intermittent continuous ecg-monitoring, in high risk primary care patients will lead to a higher incidence of AF as compared to the usual care.
To provide important information for future vaccination strategies and offer the opportunity to asses shared or unique immune responses after natural infection or vaccination, as well as to compare immune responses after infection with different…
1) EMDR is more effective in reducing symptoms of PTSD behavioral and emotional symptoms and improving quality of life in refugee children and adolescents currently living in the Netherlands, when compared to a waiting list control group. 2) KIDNET…
On TRACk, a blended intervention that prepares both patients and pharmacy technicians for two inhaler medication consultations and trains technicians in their communication will improve inhaler medication adherence and inhaler technique in patients…
Primary Objective: • To create a population pharmacokinetic model of SARS-COV-2 neutralizing antibodies as present in ConvP. • To create a population pharmacokinetic model of SARS-COV-2 neutralizing antibodies as present in Nanogam plus Secondary…
We hypothesise that patients in the intervention group will show a reduction in sedentary time of at least 60 minutes per day after the cardiac rehabilitation program, compared to a reduction of maximally 30 minutes per day in the control group.
The test product supports normal physical growth in healthy term infants
Emerging techniques measuring oxidative APAP metabolites and microRNA-122 (miR-122) could make it possible to detect paracetamol induced liver injury earlier and more precisely than currently used paracetamol plasma concentrations and clinical…
To evaluate the safety and tolerability of AP30663 in healthy males at doses up to 12mg/kg