840 results
It is hypothesised that compared to waiting list control condition, participants in the intervention improve their diet and physical activity on the short (6 months after baseline) and long-term (12 months after baseline; when the participant…
Our hypothesis is that piperacillin/tazobactam, ciprofloxacin, co-trimoxazole and doxycycline are able to penetrate hepatic cysts.
Het doel van de studie is om op de consultatiebureaus in de regio Kennemerland de haalbaarheid, kosten-effectiviteit en acceptatie van vroege opsporing naar coeliakie (door middel van case finding) bij kinderen tussen de 12 maanden en 4 jaar te…
Changing the context in which individuals make lifestyle choices has a sustained impact on the dietary intake and cardiometabolic health.
The constantly increasing number of aorto-iliac lesions in patients with end-stage renal disease (ESRD) seems to be the result of three main factors: increased recipient age, frequent atherosclerosis accompanying with end-stage renal disease and…
- It is hypothesized that a tailored, outreaching and systemic intervention promotes medication adherence - It is hypothesized that a tailored, outreaching and systemic intervention has a beneficiary effect on other medical as well as psychological…
(Experimental) participants who receive information about the availability and use of mindfulness-apps after an MBSR course: (1) report higher frequency of mindfulness practice, (2) report higher mindfulness, lower general psychopathology, and…
PMS increases the chance of problematic use of psychoactive substances. In case of problematic use of psychoactive substances the prevalence of PMS is higher than in case of non problematic use.
Patients with Alzheimer's disease have a significantly reduced function of the visual path compared to healthy people.
The proxy-patient perspective outcome has a higher level of agreement with the outcome of the self-completed EQ-5D-5L, compared with the proxy-proxy perspective outcome in mentally healthy patients.
Respiratory Syncytial Virus (RSV) is still the leading cause of hospitalization of children under 5 years of age. Currently, there is no effective treatment licensed for an ongoing RSV infection. Therefore, Intravacc develops a live-attenuated…
We hypothesize that ID is an important factor in the limitation of exercise capacity in HFpEF. Systemic low-grade inflammation does not only lead to microvascular dysfunction but also to iron deficiency. Iron deficiency has a direct effect on the…
the present study investigates whether a small-scale stay in an enriched green environment in a care center is related to a slower progression of cognitive functions, better mood, less behavioral problems, and a higher quality than if standard care…
We hypothesize that there is no difference in the number of patients experiencing partial flap loss at six months post operative.
The actual ERAS statement regarding intra- and postoperative analgesia recommends to not use thoracic epidural catheters in laparoscopic surgery anymore as a gold standard. This cohort study will investigate an alternative possibility of pain…
Stabilisation of preterm infants performing physioloigcal based cord clamping using the Concord is at least as effective as stabilisation according to the standard approach using the standard resusciation table.
To compare a ventilation strategy that uses conservative targets (PaO2 55-80 mmHg (7.3-10.7 kPa)) with one that uses conventional oxygenation targets (PaO2 110-150 mmHg (14.7-20 kPa)) for arterial oxygenation. Primary endpoint is all-cause mortality…
LRRK2 activity is linked to central mechanisms of Parkinson’s disease pathology through its role in lysosomal function, and LRRK2 kinase inhibitors, such as DNL201 (IND Number: 133665) represent a new class of therapeutics with potential to address…
1. An early screening at 1y of corrected age will identify preterm children with an increased risk of developing visual processing dysfunctions 2. Early visual rehabilitation from 1y of corrected age will benefit the visual and neurocognitive…
In this study, the primary objective is to compare MTX-PGn levels in PBMCs of RA patients with levels in RBCs and serum and to determine the correlations with clinical response. The secondary objective is to investigate route of administration-…