5 results
The main objective of this Phase IIa/b study is to demonstrate the effectof zibotentan on HVPG, and that dapagliflozin can mitigate fluid retention safety concernsregarding its use in this population.
The primary objectives of this study are:- To explore the therapeutic effect of eluxadoline in treating IBS-D in pediatric patients 6-17 years of age.- To evaluate the pharmacokinetics (PK) of eluxadoline in pediatric patients with IBS-D.- To…
Primary Efficacy Objective:To evaluate the efficacy of lenabasum compared to placebo in the treatment of SSc by assessing the American College of Rheumatology (ACR) Provisional Combined Response Index in diffuse cutaneous Systemic Sclerosis (CRISS)…
Primary efficacy objectives:To evaluate the efficacy of lenabasum 20 mg twice per day (BID) compared to placebo in the treatment of cystic fibrosis (CF) by assessing the rate of pulmonary exacerbations (PEx) using primary definition of PEx.Secondary…
· To evaluate the effect of zibotentan anddapagliflozin in combination and alone versusplacebo on UACR.