858 results
In this study, we have the following research objectives:1. To examine if NF, by applying the above mentioned AA-protocol, is an efficacious treatment for major depressive disorder. We will conduct a RCT in which active NF will be compared to sham-…
The objective of the study is to determine whether exposure to the SpectraMax light therapy device, emitting light in a combined spectra of blue/green light (460 * 570 nm) with an intensity of approximately 1300 Lux, will be more effective in…
Determining the long-term (18 months) effectiveness and cost-effectiveness of an elimination diet (ED) as the first addition to care as usual (CAU) in comparison to providing CAU only in children with ADHD (5-12 years). Hypotheses: Long-term…
The proposed study aims to investigate the effects of a psychomotor assertiveness training by means of a multicentre randomized controlled trial (RCT). Effects will be examined at the behavioural level by means of questionnaires and interviews, and…
Primary objective: To investigate the effectiveness of ongoing treatment with methylphenidate as prescribed in clinical practice beyond two years in children and adolescents. Secondary objectives:(1) to investigate the effects of discontinuation of…
The main objective of this study is to investigate the effectiveness of the self-help program compared to a waiting-list control group in reducing depressive symptoms. Secondary objectives include the investigation of moderators and mediators of…
Specific AimsAs reviewed above, childhood anxiety disorders are highly prevalent and debilitating, and there is an urgent need for improvement of current treatment strategies. An innovative, but scarcely examined, treatment option for childhood…
The primary objective of this study is: To study the effect of controlled discontinuation of long-term used risperidone, for the treatment of challenging behavior, on behaviour and health. Our hypothesis is that long-term use of risperidone for…
Study 1 is aimed to describe normative trajectories of parenting efficacy from pregnancy to early parenthood. Study 2 is focused on the question whether mental representations of attachment are protective in the context of parenting stress and its…
The aim of this study is to investigate the effectiveness of EMDR with traumatized adolescents (12-18 years) with major depressive disorder.
To investigate the impact of the multispecies probiotic product Ecologic*Barrier on neurocognitive measures of emotion and executive functioning.
Our long-range goal is to develop a comprehensive, clinically and cost effective treatment for BPD that produces both symptom remission and functional recovery. We aim to determine the role that group ST can have in the comprehensive treatment of…
(1) To investigate the effect of rTMS in a treatment set-up of 4 weeks including sham-rTMSas a control in 2 x 50 patients who have had at least two prior antidepressant therapies and psychotherapy according to the Dutch guideline of depression.(2)…
By relating valid learning fMRI phenotypes to the earliest expression of psychopathology and response to non-pharmacological self-management treatment, the project will contribute to the new innovative field of practical neuroimaging in the earliest…
The main objective of the study is to evaluate the efficacy of the *Blended Coping Cat* program in reducing anxiety levels in children diagnosed with anxiety disorders and possible ADHD, ASD, mild intellectual disability or borderline intellectual…
We aim to study the effects of PEMF on pain in fibromyalgia.
This study aims to evaluate the safety, tolerability and sedative proporties of a single dose of intransally administered dexmedetomidine in person odler than 65 years, differentiating between person using beta-blocking medication and those not…
Is there a difference in how youth experience the working alliance between the group treated with blended E-health and the group treated as usual (all face-to-face sessions)?Does the reduction of symptoms correlate with how patient experience the…
This study will investigate the effectiveness of an interactive smart phone application that provides medication reminders and motivation to take up healthy activities during daily life, with the aim to improve schizophrenic and non-affective…